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Comparatively, the L-carnitine group exhibited a lower BMI(kg/m2) (23.40(21.11-25.96) versus 22.40(20.89-24.22), P=0.005 and a reduced D3 top-quality embryo rate (%) (25.00 [0.00-60.00] versus 0.00 [0.00-50.00] P=0.018) than the control group in our non-parametric tests, as summarized in Table 1
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We found that expression of GPX4 was reduced after Cys 2 starvation and erastin treatment, further proving that ferroptosis is a primary mechanism of GSH depletion-induced cell death in RPE (Fig