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2007;22(3):659–61 Reiss AB, Anwar F, Chan ES, et al

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All the transporters like, ASCT2, SLC1A5, enzymes, like, GLS, glutamate dehydrogenase (GDH), alanine transaminase (ALT/GPT) or aspartate transaminase (AST/GOT) and metabolic intermediates associated with Gln metabolism offers chemoresistance, possibly regulated through EGFR signalling and downstream MAPK and AKT-mTOR pathway[66]

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