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Frontiers | Modulating oxidative stress and neurogenic inflammation: the role of topiramate in migraine treatment

One more realistic animal model is that induced by cecal ligation and puncture (CLP), where puncturing the cecum causes the release of fecal material in the peritoneum that results in a polymicrobial peritoneal sepsis

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"Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation." American Journal of Clinical Nutrition