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Consistently, measures of BDNF in the central nervous system (brain BDNF, b-BDNF) correlate with measures of BDNF from the periphery (serum BDNF, sBDNF) (Sartorius et al., 2009

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The Global Response Assessment Questionnaire was utilized to evaluate the patients’ perception of the effectiveness of this therapy and all 12 patients responded with a score corresponding to “significant improvement”