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doi: 10.1038/sj.mp.4001888 314 MockingRJAssiesJLokARuheHGKoeterMWVisserIet al

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discontinue use and contact the prescriber if this occurs Warnings and Precautions Warnings and Precautions Avoid waxing, laser treatments, chemical peels, or dermabrasion to areas being managed with Stella+ without first consulting the prescriber Do not use near heat sources (e.g., heating pads, saunas) immediately after applying — increased blood flow to the skin may increase absorption and irritation Inform all healthcare providers that this cream is being used, especially before undergoing any facial procedures Do not apply during periods of significant skin barrier disruption (e.g., after laser resurfacing, chemical peels, or active sunburn) without specific provider guidance Pregnancy — topical tretinoin and estriol are nominally absorbed into circulation but are generally avoided during pregnancy Breastfeeding — use with caution