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40 juvenile male Western Albino rats (aged 3–4Ramaekers et al., weeks) received oral PPA at 250 mg/kg/for 3 days to induce autism-like features, followed by 3 weeks of probiotic treatment with Bifidobacterium infantis , Lactobacillus bulgaricus, or a commercial probiotic mixture (all at 0.2 g/kg)

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These gene sets were not enriched in GPX4 perturbed cells in the absence of giredestrant, consistent with the screen results that identified GPX4 as a giredestrant-dependent vulnerability (Supplementary Fig